USMLE Cell Injury, Cell Death, & Cancer High Yield Rating List

10 – Metastasis

8 – Free Radicals

8 – Necrosis

8 – Reversible vs. Irreversible Cell Injury

7 – Cellular Adaptions

7 – Apoptosis

5 – Amyloidosis

5 – Cell Cycle

4 – p53 Tumor Suppressor

3 – Bcl-2 Oncogene

2 – MYC Oncogene

2 – rb Tumor Suppressor

1 – HER2/Neu Oncogene

1 – E6 & E7 Oncogenes

1 – BRCA 1 & 2 Tumor Suppressor

 

Low Yield/No Yield:

Other Oncogenes (Ras, Ret, Ki-67, C-Kit …)

Other Tumor Suppressors (APC, DCC, NF-2…)

Telomeres

Epidemiology of which cancers are most common

Pyknosis/Karyorrhexis/Karyolsis

Fibrinoid Necrosis

Psommoma Bodies

Fenton Reaction

Creation of free radicals by ionizing radiation

Dialysis associated amyloid

Amylin Amyloid in diabetes

TNM system & How to determine specific grade/stage

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